Scientists are uncovering how GLP-1 drugs like Ozempic and Wegovy act on brain regions that control hunger, nausea, pleasure-based eating, and thirst. These discoveries may help create treatments that keep the benefits of weight loss while reducing unwanted side effects.

Researchers have created one of the most detailed virtual mouse cortex simulations ever achieved by combining massive biological datasets with the extraordinary power of Japan’s Fugaku supercomputer. The digital brain behaves like a living system, complete with millions of neurons and tens of bill...

Researchers have discovered chemical traces of life in rocks older than 3.3 billion years, offering a rare look at Earth’s earliest biology. By combining advanced chemical methods with artificial intelligence, scientists were able to detect faint molecular patterns left behind long after the origi...

Rutgers scientists found that metformin can blunt many of the metabolic and cardiovascular improvements normally produced by exercise. Participants who took the drug saw reduced gains in fitness, blood vessel function, and glucose control. The interference may stem from how metformin affects mitocho...

Chronic kidney disease has surged to nearly 800 million cases and is now among the top causes of death worldwide. The condition is heavily linked to diabetes, hypertension, and obesity, and often goes unnoticed until late stages. Many countries lack access to dialysis and transplants, leaving millio...

Cutting-edge simulations show that Enceladus’ plumes are losing 20–40% less mass than earlier estimates suggested. The new models provide sharper insights into subsurface conditions that future landers may one day probe directly.

Scientists discovered that alcohol activates a sugar-producing pathway in the body, creating fructose that may reinforce addictive drinking. The enzyme responsible, KHK, appears to drive both alcohol cravings and liver injury. When this enzyme was blocked in mice, their drinking decreased and their ...

Scientists are turning venom, radioisotopes, engineered proteins, and AI into powerful new tools against cancer. From Amazonian scorpions yielding molecules that kill breast cancer cells as effectively as chemotherapy, to improved fibrin sealants and custom-grown bioactive factors, researchers are p...

Researchers developed a new nano-micelle formulation, CBD-IN, that finally gets CBD into the brain effectively. In mice, it relieved neuropathic pain quickly and didn’t cause the usual movement or memory side effects. Surprisingly, the pain relief didn’t use typical cannabinoid receptors, instea...

Scientists built a tiny clock from single-electron jumps to probe the true energy cost of quantum timekeeping. They discovered that reading the clock’s output requires vastly more energy than the clock uses to function. This measurement process also drives the irreversibility that defines time’s...

Scientists mapped the Bas63 bacteriophage in unprecedented detail, uncovering how its tail machinery infects bacteria. The structure reveals rare whisker-collar features and distant evolutionary ties reaching back billions of years. These insights could guide new phage therapies and innovations in m...

Scientists have revealed that Hawaiian monk seals produce far more underwater vocalizations than previously believed. Their newly discovered 25-call repertoire includes complex combinations and a rare foraging-related call. These findings highlight an intricate acoustic world unfolding beneath the w...

During years of scarce fish, African penguins crowd into the same areas as commercial fishing vessels, heightening competition for dwindling prey. A new metric called “overlap intensity” shows how many penguins are affected and is already shaping improved conservation policies.

A new dual-light microscope lets researchers observe micro- and nanoscale activity inside living cells without using dyes. The system captures both detailed structures and tiny moving particles at once, providing a more complete view of cellular behavior. Its creators tested it by analyzing changes ...

Older adults who regularly listen to or play music appear to have significantly lower risks of dementia and cognitive decline. The data suggests that musical engagement could be a powerful, enjoyable tool for supporting cognitive resilience in aging.

Researchers have uncovered that SerpinB3, typically linked to severe cancers, is also a key player in natural wound healing. The protein drives skin cell movement and tissue rebuilding, especially when paired with next-generation biomaterial dressings. Its newfound role explains why cancer cells exp...

People are more likely to believe lies when there’s the possibility of a reward. Neuroimaging shows that the brain shifts into reward or risk mode depending on whether the context involves a gain or a loss. Friends show synchronized brain activity that can predict successful deception. Social bond...

Ultra-processed foods, already known for their links to health problems in adults, are now shown to harm young adults too, disrupting blood sugar regulation long before illness appears. A four-year USC study following 85 participants found that even modest increases in UPF consumption drove up the r...

Across the planet, animals are increasingly suffering from chronic illnesses once seen only in humans. Cats, dogs, cows, and even marine life are facing rising rates of cancer, diabetes, arthritis, and obesity — diseases tied to the same factors affecting people: genetics, pollution, poor nutritio...

Hawaiian short-finned pilot whales are surprisingly voracious hunters, diving hundreds of meters beneath the Pacific to snatch squid in the dark. By tagging and tracking eight whales, researchers uncovered just how much energy these deep-sea forays require—and how many squid the whales must eat to...

Astronomers have, for the first time, recorded the moment a star’s explosion broke through its surface. The nearby supernova, SN 2024ggi, revealed a surprisingly olive-shaped blast when studied with ESO’s Very Large Telescope. The discovery helps scientists better understand the forces that driv...

The “Seven Sisters” have far more relatives than anyone imagined. Using NASA and ESA space telescopes, astronomers found thousands of hidden stars linked to the Pleiades, forming a colossal stellar complex. The discovery expands the cluster’s size by a factor of 20 and offers a new way to trac...

Penn State scientists identified a striking rise in melanoma across several Pennsylvania counties dominated by cropland and herbicide use. The elevated risk persisted even after factoring in sunlight, suggesting an environmental influence beyond the usual expectations. Researchers warn that drifting...

Researchers combined deep learning with high-resolution physics to create the first Milky Way model that tracks over 100 billion stars individually. Their AI learned how gas behaves after supernovae, removing one of the biggest computational bottlenecks in galactic modeling. The result is a simulati...

LHAASO has uncovered that micro-quasars, black holes feeding on companion stars, are powerful PeV particle accelerators. Their jets produce ultra-high-energy gamma rays and protons that exceed long-held expectations. Precise cosmic-ray measurements reveal a new high-energy component, suggesting mult...

Electrons can freeze into strange geometric crystals and then melt back into liquid-like motion under the right quantum conditions. Researchers identified how to tune these transitions and even discovered a bizarre “pinball” state where some electrons stay locked in place while others dart aroun...

Researchers at KRISS observed water’s rapid freeze–melt cycles under ultrahigh pressure and discovered Ice XXI, the first new ice phase found in decades. Using advanced high-pressure tech and microsecond XFEL imaging, they uncovered complex crystallization pathways never seen before. Ice XXI’s...

Researchers found that ancient hominids—including early humans—were exposed to lead throughout childhood, leaving chemical traces in fossil teeth. Experiments suggest this exposure may have driven genetic changes that strengthened language-related brain functions in modern humans.

Dark matter may be invisible, but scientists are getting closer to understanding whether it follows the same rules as everything we can see. By comparing how galaxies move through cosmic gravity wells to the depth of those wells, researchers found that dark matter appears to behave much like ordinar...

Chimps may revise their beliefs in surprisingly human-like ways. Experiments showed they switched choices when presented with stronger clues, demonstrating flexible reasoning. Computational modeling confirmed these decisions weren’t just instinct. The findings could influence how we think about le...

Researchers have sequenced the oldest RNA ever recovered, taken from a woolly mammoth frozen for nearly 40,000 years. The RNA reveals which genes were active in its tissues, offering a rare glimpse into its biology and final moments. Surprisingly, the team also identified ancient microRNAs and rare ...

Scientists discovered that a week of full submergence is enough to kill most rice plants, making flooding a far greater threat than previously understood. Intensifying extreme rainfall events may amplify these losses unless vulnerable regions adopt more resilient rice varieties.

Scientists found that people who use both cannabis and tobacco show a distinct brain pattern tied to mood and stress regulation. Their scans revealed higher levels of an enzyme that reduces a natural feel-good molecule in the brain. This imbalance may help explain why co-users experience more anxiet...

Researchers found that tau proteins don’t jump straight into forming Alzheimer’s-associated fibrils—first they assemble into soft, reversible clusters. When the clusters were dissolved, fibril growth was almost entirely suppressed. This reveals a promising new strategy: stop the precursors, st...

Researchers digitally mapped ancient Chinese tombs and discovered that their distribution mirrors shifts in political stability, population movements, and natural geography. Peaceful, prosperous eras produced more elaborate and numerous burial sites, while wartime periods saw far fewer. Tomb cluster...

Scientists uncovered Australia’s oldest known crocodile eggshells, revealing the secret lives of ancient mekosuchine crocodiles that once dominated inland ecosystems. These crocs filled surprising niches, including terrestrial stalking and possibly tree-dropping ambushes.

Genetic, isotopic, and forensic evidence has conclusively identified the remains of Duke Béla of Macsó and uncovered remarkable details about his life, ancestry, and violent death. The study reveals a young nobleman with Scandinavian-Rurik roots who was killed in a coordinated, emotionally charged...

A massive, well-preserved impact crater has been uncovered in Guangdong, revealing the signature of a powerful meteorite strike during the Holocene. Measuring 900 meters across, it dwarfs other known craters from the same era. Shock-damaged quartz confirms the intense forces involved. Its survival i...

Scientists have finally confirmed a powerful coronal mass ejection from another star, using LOFAR radio data paired with XMM-Newton’s X-ray insights. The eruption blasted into space at extraordinary speeds, strong enough to strip atmospheres from close-orbiting worlds. This suggests planets around...

Laser light can physically distort Janus TMD materials, revealing how their asymmetrical structure amplifies light-driven forces. These effects could power breakthroughs in photonic chips, sensors, and tunable light technologies.

Scientists have decoded the atomic-level secrets behind catalysts that turn propane into propylene. Their algorithms reveal unexpected oxide behavior that stabilizes the catalytic reaction by clustering around defective metal sites. The findings could help streamline industrial chemistry and inspire...

Researchers in Greenland used a 10-kilometer fiber-optic cable to track how iceberg calving stirs up warm seawater. The resulting surface tsunamis and massive hidden underwater waves intensify melting at the glacier face. This powerful mixing effect accelerates ice loss far more than previously unde...

Hektoria Glacier’s sudden eight-kilometer collapse stunned scientists, marking the fastest modern ice retreat ever recorded in Antarctica. Its flat, below-sea-level ice plain allowed huge slabs of ice to detach rapidly once retreat began. Seismic activity confirmed this wasn’t just floating ice ...

Researchers have created a prediction method that comes startlingly close to real-world results. It works by aiming for strong alignment with actual values rather than simply reducing mistakes. Tests on medical and health data showed it often outperforms classic approaches. The discovery could resha...

Exercise appears to spark a whole-body anti-aging cascade, and scientists have now mapped out how it happens—and how a simple oral compound can mimic it. By following volunteers through rest, intense workouts, and endurance training, researchers found that the kidneys act as the hidden command cen...

Ultra-endurance athletes can push their bodies to extraordinary extremes, but even they run into a hard biological wall. Researchers tracked ultra-runners, cyclists, and triathletes over weeks and months, discovering that no matter how intense the effort, the human body maxes out at about 2.5 times ...

A newly detected super-Earth just 20 light-years away is giving scientists one of the most promising chances yet to search for life beyond our solar system. The discovery of the exoplanet orbiting in the habitable zone of its star was made possible by advanced spectrographs designed at Penn State an...

Researchers engineered “gyromorphs,” a new type of metamaterial that combines liquid-like randomness with large-scale structural patterns to block light from every direction. This innovation solves longstanding limitations in quasicrystal-based designs and could accelerate advances in photonic c...

Bumble bees battling invasive Argentine ants may win individual fights but ultimately lose valuable foraging time, putting pressure on colonies already strained by habitat loss, disease, and pesticides. New research shows bees often avoid ant-occupied feeders, and while their size helps them win one...

Researchers have uncovered surprising evidence that anxiety may be controlled not by neurons but by two dueling groups of immune cells inside the brain. These microglia act like biological pedals—one pushing anxiety forward and the other holding it back.