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1 August 2020, 9:34 pm

Pre-Clinical Test of Johnson & Johnson Vaccine Shows It Protected Monkeys from Covid-19 science.slashdot.org

Pre-Clinical Test of Johnson & Johnson Vaccine Shows It Protected Monkeys from Covid-19




"Johnson & Johnson's experimental coronavirus vaccine protected macaque monkeys with a single shot in a pre-clinical study, potentially gaining on other vaccines that are further along in testing but require two doses over time," reports Bloomberg: Five of six primates exposed to the pandemic-causing pathogen were immune after a single injection. The exception showed low levels of the virus, according to a study published in the medical journal Nature... The health-care behemoth kick-started human trials on July 22 in Belgium and in the U.S. earlier this week. Although other vaccine-makers have moved more quickly into development, with AstraZeneca having already administered its experimental vaccine to almost 10,000 people in the U.K., gaining protection with a single dose could prove an advantage in the logistical challenge of rolling out massive vaccination programs worldwide.... The primate data show that the coronavirus vaccine candidate generated a strong antibody response, and provided protection with only a single dose, said Paul Stoffels, the drugmaker's chief scientific officer. J&J aims to embark on the last phase of tests in September, compressing the traditional timeline as it races against others including AstraZeneca, Moderna Inc., Pfizer Inc. and GlaxoSmithKline Plc for a shot to end the pandemic.... The New Brunswick, New Jersey-based drugmaker will test both a one-dose coronavirus shot, and a shot coupled with a booster in its early-stage studies of more than 1,000 adults, which launched this month.

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